designed to create a strong electromagnetic field around themselves that helps

capture nanoparticles in close vicinity.

10.4

Challenges

Although the conceptualisation of nanodentistry involves scientific thinking and

engineering models, its implementation in a practical sense is limited by the follow-

ing challenges:

1. Production challenges

•

Precision in positioning and assembly of nano-molecules

•

Coordinating the functioning of the individual nanoparticles simultaneously

and effectively

2. Biological challenges

•

Biocompatibility of the nanomaterial

•

Safety assessment

3. Social challenges

•

Economic barrier

•

Acceptance by the patient

10.5

Conclusion

Nanotechnology in clinical dentistry has achieved milestones in the fabrication of

nanomaterials, especially in restorative dentistry. Current research is focussed on the

development of nanorobots in the diagnosis and treatment of oral cancer. More

research related to dental health care should focus on drug delivery systems. The

safety profile of nanomaterials should be strictly assessed to ascertain that their use

causes no adverse effects. Overall, the application of nanotechnology in dental

practice promises highly advanced diagnostic and therapeutic services for improved

oral health care.

References

Aeran H, Kumar V, Uniyal S, Tanwer P (2015) Nanodentistry: is just a fiction or future. J Oral Biol

Craniofac Res 5:207–211

Afkhami F, Pourhashemi SJ, Sadegh M, Salehi Y, Fard MJ (2015) Antibiofilm efficacy of silver

nanoparticles as a vehicle for calcium hydroxide medicament against Enterococcus faecalis. J

Dent 43:1573–1579

Allen TM, Cullis PR (2013) Liposomal drug delivery systems: from concept to clinical

applications. Adv Drug Deliv Rev 65:36–48

Bayda S, Adeel M, Tuccinardi T, Cordani M, Rizzolio F (2019) The history of nanoscience and

nanotechnology: from chemical-physical applications to nanomedicine. Molecules 25:112

150

K. Gauba et al.